Description
Technical Parameters
Hypoxanthine Monosodium Salt
CAS No.:45738-97-4
Synonyms
Sodium 6-oxo-3,6-dihydropurin-7-ide;
Hypoxanthine sodium 98%;
3,7-dihydropurin-6-one,sodium;6H-Purin-6-one,1,2,3,9-tetrahydro-,sodium salt (1:1)
Chemical structural formula

Products Description
|
Appearance |
A white or off -white crystalline powder |
|
Solubility |
The 0.5% aqueous solution was dissolved |
|
Loss on drying |
≤1.0% |
|
pH |
9.0~10.5 |
|
Assay |
≥98.0% |
|
Molecular Weight |
256.26 |
|
Molecular Formula |
C5H4N4NaO |
Storage
Room temprature, tightly closed, protected from humidity.
Package
10g/bag,100g/bag,1kg/bag,5kg/drum,25kg/drum.
Drum packing: 2 plastic PE bags innerside + paper drum outside.
Service
Customized drum/barrel/bottle packaging acceptable.
Hypoxanthine Monosodium Salt NMR

Application
1.Pharmaceutical Intermediate (Primary Use)
Used for the synthesis of xanthine oxidase inhibitors (such as febuxostat and allopurinol) for the treatment of gout and hyperuricemia.
Applied in the preparation of purine antiviral and antitumor drugs (such as mercaptopurine and azathioprine).
2.Biochemical Research and Cell Culture
Serves as a purine metabolic substrate and reference standard for the activity detection of xanthine oxidase (XO) and research on uric acid formation mechanisms.
Used as an additive in cell culture media; participates in the nucleotide salvage pathway to support cell growth.
3.Organic Synthesis Building Block
Used to construct purine ring derivatives for new drug research and development, pesticide synthesis, and biological probe design.
4.Analytical Reference Standard
Applied for the calibration of HPLC, NMR and LC-MS; used for the quantitative detection of hypoxanthine and uric acid in biological samples (serum, urine).
FAQ
FAQ about 6-Hydroxypurinate
Q: Advantages of Sodium 6-Hydroxypurinate over Hypoxanthine
A: Compared with hypoxanthine, sodium 6-hydroxypurinate has the following advantages:
Remarkably improved water solubility
Hypoxanthine is slightly soluble in water, while its sodium salt is easily soluble, making solution preparation much more convenient.
Higher stability
It features better stability, easier storage and transportation, and is suitable for industrial scale-up production.
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