Description
Technical Parameters
Thymidine
Synonyms:1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;Thymidine For Biochemistry;
2'-Deoxythymidine;2,4(1H,3H)-Pyrimidinedione,1-(2-deoxy-beta-D-ribofuranosyl)-5-methyl-;Doxribtimine;SS-THYMIDINE;β-Thymidine;Thymidine>99%;DThyd;dT
The development history of thymidine
The development history of thymidine epitomizes the evolution from biochemistry to pharmaceutical industry and finally to rare disease therapy:
1893: First isolated, ushering in the era of nucleic acid research;
1950–1960: Mechanisms elucidated, becoming a core tool in cell biology;
1987: Approval of Zidovudine(AZT) revolutionized the treatment history of HIV;
2025: Launch of KYGEVVI(doxecitine/doxribtimine) put an end to the "no treatment available" predicament for TK2d.

Specifications
|
Appearance |
A white or almost white crystalline powder |
|
Solution Clarity Test |
Clear |
|
Purity(HPLC) |
≥98.00% |
|
Assay(HPLC) |
≥98.50% |
|
Specific optical rotation |
+17.5°~+19.5° |
|
Water by K.F. |
≤0.50% |
|
Melting point |
183℃~190℃ |
|
Residue ignition |
≤0.30% |
|
Related substances |
2'-deoxyuridine ≤0.05% |
|
Thymine ≤1.00% |
|
|
Single impurity ≤0.10% |
|
|
Total impurity ≤1.50% |
Application
- Used for anti-AIDS drugs (such as zidovudine, stavudine)
- 2025-11-03: The FDA approved KYGEVVI (deoxycytidine + deoxythymidine) for the treatment of thymidine kinase 2 deficiency (TK2d). It is the world's first drug specifically for this ultra-rare mitochondrial myopathy, reducing the risk of death by 86%.
- 2026-04-15: The European Commission granted simultaneous approval to KYGEVVI, indicated for children and adults with disease onset under 12 years of age, making it the first TK2d therapy authorized in the EU.
Production Process
We are equipped with mature production platforms of chemical synthesis and biological fermentation.With advanced process control, we ensure superior product purity, stable supply capacity and full compliance with pharmaceutical production requirements.

Other Information
Storage:Room temprature, tightly closed, protected from humidity.
Package:1kg/bag,5kg/drum, 25kg/drum
Drum packing: 2 plastic PE bags innerside + paper drum outside.
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